1. Vain is used as an adjective to mean: without much value or significance; excessively proud or concerned about one's own appearance, personal qualities or achievements. The expression "in vain" as in "I argued in vain" means without achieving one's purpose.
2. Vane, a noun, most frequently refers to a device used to determine the direction of wind.
3. Vein as a noun refers to blood vessels that carry blood from various body parts to the heart. Similarly, veins also are tissues that form the principal framework of a leaf or line-markings in marble or rocks. Also, vein means a condition or manner (as in "in a serious vein.") As a verb vein means to supply with veins.
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